Aortoiliac occlusion due to atherosclerosis is known to occur in elder
ly people, Two unique cases are documented here in which aortoiliac oc
clusion was observed in young men. These patients had no identifiable
risk factors for developing atherosclerotic thrombosis except for the
lupus anticoagulant, an immunoglobulin associated with thromboembolic
episodes. Although previously the lupus anticoagulant has been reporte
d to cause thrombosis only in relatively small-sized arteries or veins
, it may also be associated with aortoiliac atheromatous occlusion in
young men.