Tonsillar application of formalin-killed cells of Streptococcus sobrinus reduces experimental dental caries in rabbits

Authors
Fukuizumi, T Inoue, H Tsujisawa, T Uchiyama, C
Citation
T. Fukuizumi et al., Tonsillar application of formalin-killed cells of Streptococcus sobrinus reduces experimental dental caries in rabbits, INFEC IMMUN, 67(1), 1999, pp. 426-428
Citations number
21
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
67
Issue
1
Year of publication
1999
Pages
426 - 428
Database
ISI
SICI code
0019-9567(199901)67:1<426:TAOFCO>2.0.ZU;2-T
Abstract
Living Streptococcus sobrinus cells were orally inoculated into nonimmune r abbits and rabbits immunized with formalin-killed cells of S. sobrinus thro ugh tonsillar application to examine the anticaries potential of this metho d of immunization. The living S. sobrinus cell numbers and the caries areas in the rabbits immunized by tonsillar application decreased to a level one -fifth of that in nonimmune rabbits.