A quadruply-bonded dirhenium complex bridged by two N-1/N-6 adenate ligands

Authors
Prater, ME Mindiola, DJ Ouyang, X Dunbar, KR
Citation
Me. Prater et al., A quadruply-bonded dirhenium complex bridged by two N-1/N-6 adenate ligands, INORG CH C, 1(12), 1998, pp. 475-477
Citations number
28
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
INORGANIC CHEMISTRY COMMUNICATIONS
ISSN journal
13877003 → ACNP
Volume
1
Issue
12
Year of publication
1998
Pages
475 - 477
Database
ISI
SICI code
1387-7003(199812)1:12<475:AQDCBB>2.0.ZU;2-9
Abstract
The first structurally characterized example of a metal-metal bonded comple x bridged by the DNA nucleobase adenine through the N1, N6 positions is rep orted. The new dirhenium compound, Re-2(O2CCH2CH3)(2)(9-EtA)(2)Cl-2 . CH3CH 2O . C6H14, binds to adenine at the sites where thymine normally engages in Watson-Crick base-pairing. Such chemistry, if it occurs in vivo, could pla y a role in the carcinostatic activity of tetrapropionatodirhenium complexe s that are known to inhibit DNA replication. (C) 1998 Elsevier Science S.A. All rights reserved.