Children with acute mastoiditis with periosteitis are conventionally hospit
alized for parenteral antibiotics and/or surgical treatment. However, if po
ssible, effective and safe outpatient treatment is desirable. During a 36-m
onth period, outpatient parenteral antibiotic therapy (once daily i.m. ceft
riaxone) was evaluated in 32 children with acute mastoiditis, with clinical
evidence of periosteitis. Inclusion criteria included otomicroscopic evide
nce of acute otitis media (AOM), displacement of the pinna, retroauricular
swelling, erythema and tenderness. The treatment consisted of wide myringot
omy and administration of i.m. antibiotics. Daily visits, by a combined tea
m of an otolaryngologist and pediatric infectious disease specialist, were
considered essential. Fourteen children (43%) were treated initially in the
hospital (and subsequently as outpatients) and 18 (57%) children were trea
ted entirely as outpatients. Mean duration of outpatient treatment was 7 da
ys (range: 4-10). The overall clinical cure rate was 96.8%. One child under
went simple mastoidectomy. No serious side effects were observed. Our data
suggests that many children with acute mastoiditis with periosteitis can be
managed successfully and safely as outpatients by a combined team of otola
ryngologists and infectious disease specialists. (C) 1998 Published by Else
vier Science Ireland Ltd. All rights reserved.