This study was designed to evaluate the differences in clinical findings be
tween patients with and without Q waves in acute myocarditis. Among a total
of 24 patients, eleven patients had Q waves and thirteen did not. Echocard
iographic findings, in-hospital complications and follow-up results were co
mpared between the two groups. In the acute stage, the Q wave group showed
significantly higher creatine kinase (CK) values and a more impaired left v
entricular ejection fraction than the non-Q wave group (40 +/- 11% vs 57 +/
- 10%, p < 0.001). Transient left ventricular hypertrophy was also prominen
t in the Q wave group. The incidence of cardiogenic shock (55%) and conduct
ion disturbances (64%) were higher in the Q wave group than in the non-Q wa
ve group (0% and 15%, respectively). In-hospital mortality rate was 27% in
the Q wave group and 8% in the non-Q wave group, respectively. Since rapid
improvement occurred in survivors with Q waves, long-term prognosis was fav
orable for the two groups. In conclusion, Q waves might indicate a more sev
ere course in early illness.