Current practices vary regarding the approach to small polyps discovered du
ring screening flexible sigmoidoscopy. The most common practice is to perfo
rm colonoscopy whenever any adenoma is detected, a strategy that generally
uses biopsy of polyps less than or equal to 5 mm in size. However, data sug
gest that tubular adenomas < I cm in size in the distal colon have less pre
dictive value than other distal adenomas for advanced adenomas in the proxi
mal colon. Thus, some centers reserve colonoscopy for distal adenomas with
tubulovillous or villous histology, >1 cm in size, or with high-grade dyspl
asia. At the other end of the spectrum, another school of thought advocates
screening colonoscopy, recognizing that most patients with advanced proxim
al adenomas do not have polyps in their distal colon. Advocates of this app
roach use any excuse to perform colonoscopy, whether it be a positive fecal
occult blood test, minor symptoms, or small polyp at flexible sigmoidoscop
y, even if hyperplastic. This review describes the history of the controver
sy regarding management of findings at flexible sigmoidoscopy, the data per
tinent to the controversy, and the basis for the three approaches described
above, all of which are currently within the standard of medical care.