Objective: The carbon monoxide (CO) smoke component from tissue pyrolysis w
as evaluated for peritoneal ab sorption in patients undergoing laparoscopy
to determine its effects and ability to be detected in peripheral blood. Su
mmary Background Data: Previous studies have demonstrated changes in periph
eral methemoglobin levels as a result of peritoneal absorption of laser smo
ke. Methods: Fifty patients had preoperative, intraoperative, and postopera
tive levels of carboxyhemoglobin (COHb) and pulse oximetry evaluated, The c
ontrol group (25) had no laser or cautery used and the study group (25) had
carbon dioxide laser used during the laparoscopic procedures. Results: The
control group showed no change in COHb, or inh a-abdominal CO levels, befo
re, during, and after the procedures, and no change in blood CO or pulse ox
imetry reading. The laser smoke group showed a statistically significantly
elevated (p < .05) peripheral blood COHb levels, a significant increase in
intra-abdominal CO concentration, and a lack of correlation of pulse oximet
ry and blood oxygen saturation experiments. Conclusions: CO is created in e
xtremely large quantities during laser use at laparoscopy and is absorbed t
hrough the peritoneal cavity, Symptoms of smoke poisoning can be seen with
these elevations. Continuous or intermittent removal of smoke produced from
laser use is recommended.