Cytotoxic effects of different concentrations of neutral and alkaline EDTAsolutions used as root canal irrigants

Authors
Koulaouzidou, EA Margelos, J Beltes, P Kortsaris, AH
Citation
Ea. Koulaouzidou et al., Cytotoxic effects of different concentrations of neutral and alkaline EDTAsolutions used as root canal irrigants, J ENDODONT, 25(1), 1999, pp. 21-23
Citations number
19
Categorie Soggetti
Dentistry/Oral Surgery & Medicine
Journal title
JOURNAL OF ENDODONTICS
ISSN journal
00992399 → ACNP
Volume
25
Issue
1
Year of publication
1999
Pages
21 - 23
Database
ISI
SICI code
0099-2399(199901)25:1<21:CEODCO>2.0.ZU;2-#
Abstract
The cytotoxic effects of neutral and alkaline EDTA solutions were evaluated and compared with those of sodium hypochlorite solution using an establish ed cell line: L929, Cytotoxicity was assessed by a quantitative technique a t five observation periods (1, 3, 6, 12, and 24 h), All tested agents showe d moderate to severe cytotoxicity in the present experimental model in a co ncentration-dependent manner.