Metabolites from the sponge-associated bacterium Micrococcus luteus

In an ongoing survey of the bioactive potential of microorganisms associate d with marine invertebrates, the extract of the sponge-associated bacterial strain Micrococcus luteus was found to exhibit potent antimicrobial activi ty. The previously known synthetic 2,4,4'-trichloro-2'-hydroxydiphenylether was found to be responsible for the antimicrobial activity. The major meta bolite isolated was a new acyl-l-(acyl-6'-mannobiosyl)-3-glycerol.