Bone mineral density and depression: A community study in women

In a community sample of 102 Portuguese white women we evaluated the relati onship between osteoporosis and indexes of psychopathology and well-being. Depressive symptoms were assessed by the Beck Depression Inventory (BDI), p sychopathology by the Hopkins Symptom Checklist-90 Revised (SCL-90-R), and quality of life using the Psychological General Well-Being Index. A questio nnaire comprising social, demographic, clinical, and behavioral characteris tics was also used. The sample prevalence of osteoporosis was 47.1%. Women with osteoporosis presented significantly higher scores on the total BDI (1 6+/-9 vs. 13+/-10, p=0.045) and lower scores in the hostility (0.8+/-0.6 vs . 1.2+/-0.7, p=0.012) and phobic anxiety (1.1+/-0.8 vs. 1.5+/-0.9,p=0.041) subscales of the SCL-90-R. No differences were found regarding mean general well-being scores (62+/-17 vs. 64+/-19, p=0.665). This study showed that w omen with osteoporosis have significantly higher levels of depressive sympt oms and a corresponding higher prevalence of depression, independent of oth er factors strongly associated with osteoporosis, such as age or body mass index. (C) 1998 Elsevier Science Inc.