Cooling effects of topicals - present results and testing methods in vivo and in vitro

Authors
Thoma, K Korting, HC Thoma-Greber, E
Citation
K. Thoma et al., Cooling effects of topicals - present results and testing methods in vivo and in vitro, PHARMAZIE, 53(12), 1998, pp. 813-819
Citations number
23
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
53
Issue
12
Year of publication
1998
Pages
813 - 819
Database
ISI
SICI code
0031-7144(199812)53:12<813:CEOT-P>2.0.ZU;2-1
Abstract
The cooling effect of topicals has been used in the dermatological therapy as "physical effect" on the skin for more than hundred years. This effect o f dermatologicals releasing free water is widely accepted, but current know ledge does not correspond to today's possibilities of experimental thermogr aphic tests in man. The present paper describes the results published up to now and the current testing methods in vivo and in vitro.