Synthesis of lipophilic keto acids by acylation of alkylbenzenes as potential inhibitors of phospholipase A(2)

Authors
Nuhn, P Radman, M Hermann, A Marx, K
Citation
P. Nuhn et al., Synthesis of lipophilic keto acids by acylation of alkylbenzenes as potential inhibitors of phospholipase A(2), PHARMAZIE, 53(12), 1998, pp. 825-829
Citations number
15
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHARMAZIE
ISSN journal
00317144 → ACNP
Volume
53
Issue
12
Year of publication
1998
Pages
825 - 829
Database
ISI
SICI code
0031-7144(199812)53:12<825:SOLKAB>2.0.ZU;2-B
Abstract
A series of lipophilic keto acids were synthesized by acylation of alkylben zenes with malonic, succinic, glutaric, methylsuccinic, methylglutaric and itaconic anhydride and tested against inhibition of phospholipase A(2).