The purpose of this study was to examine the effects of intralesional bare
fiber photocoagulation with the KTP and Nd:YAG lasers on periorbital hemang
iomas of infancy. Initial reports by Apfelberg and Gregory suggest that int
ralesional laser therapy may have a role in the treatment of hemangiomas. I
ntralesional photocoagulation may be preferred to superficial laser treatme
nt for several reasons. It may decrease cutaneous skin damage and more effe
ctively reduce bulky, deep lesions. Twenty-three patients with periorbital
hemangiomas were treated (KTP, n = 7; Nd:YAG, n = 16). An 18-g Angiocath wa
s placed into the lesion to pass the fiber through. Laser energy was delive
red by means of a 0.6-mm bare fiber at 10 to 15 J (KTP) or 75 (Nd:YAG). Tre
atments were done under general anesthesia. Patients were followed closely
for 1 month and then monthly to assess results and complications. Results a
re as follows: 61 percent demonstrated 50-percent or more reduction at 3 mo
nths; 22 percent demonstrated 50-percent or more reduction in 3 to 8 months
, i.e., 83 percent of patients had 50-percent or more reduction within 8 mo
nths. To achieve these results, two patients required two treatments. The r
emaining 17 percent had 10- to 14-percent reduction at 1 to 3 months. Two o
f these patients had two treatments. A subgroup of patients had a very dram
atic response. Thirty-five percent (8 of 23) had 50- to 90-percent reductio
n in 1 month. It is unclear why these patients responded so dramatically. W
e expected some ulceration during the healing phase. Seventeen percent deve
loped ulceration. Complications were limited (4 percent) to one wound infec
tion. Intralesional photocoagulation treatment with the KTP and Nd:YAG lase
rs is effective and safe for the treatment of periorbital hemangiomas in th
e majority of patients with minimal complications. Further study is necessa
ry to identify factors that result in dramatic or limited responses.