ELEVATION OF THE LEVEL OF AUTOANTIBODIES TO NERVE GROWTH-FACTOR IN BLOOD-SERUM OF CHILDREN WITH SCHIZOPHRENIA

The level of autoantibodies (AAB) to nerve growth factor (NGF) was exa mined in blood of mentally healthy children, children with early child ren schizophrenia as well as with Canner's and Asperger's syndromes to o. The elevated titer of AAB to NGF was determined in blood of childre n with acute, active state of disease; meanwhile the same titer wasn't changed in the state of stable remission or steady defective state as compared with control group. The correlation was found between the le vel of AAB to NGF and the degree of disease progression. The correlati ons which were revealed between AAB to NGF level and peculiarities of the clinical state of patients permitted to use this index as the obje ctive marker of both the acuteness and the severity of the patient's s tate.