Id. Kozlov et al., CHANGES IN RISK PROFILE AND MORTALITY IND UCED BY IMPLICATION OF A 5-YEAR PROGRAM OF ISCHEMIC-HEART-DISEASE PREVENTION, Terapevticeskij arhiv, 69(1), 1997, pp. 14-17
Multifactorial prophylaxis on the individual basis was conducted for 5
years among the population of 2047 males aged 40-59 years with ischem
ic heart disease (IHD) or its risk factors. Compared to the comparison
group of 2101 subjects, in the study group the investigators achieved
a 37%; reduction in the mean population profile of myocardial infarct
ion risk due to less prevalence of 3 main risk factor: arterial hypert
ension, low physical activity, smoking. Unbalance of the groups by age
and education made the effect of the prevention measures on cardiovas
cular mortality menostrable only at statistical Kox's model.