Treatment of endometrial hyperplasia with hysteroscopic resection

Study Objective: To evaluate the efficacy and the safety of endometrial hys teroscopic resection in the treatment of endometrial hyperplasia without at ypia. Participants: Seventy three women, 40 to 78 years old, with histologically proven endometrial hyperplasia without atypia. Intervention: transcervical hysteroscopic endometrial resection under gener al or spinal anaesthesia. Main Outcome Measures: Efficacy of treatment was based on hysteroscopic and histological regression of endometrial hyperplasia and subjectively assess ed uterine blood loss. Safety was evaluated by adverse events. Results: 45 cycling women had experienced complete remission of uterine ble eding, and none had persistence of endometrial hyperplasia during follow up . Three underwent hysterectomy. Atrophic endometrium was present in menopau sal women. Conclusion: Endometrial resection was effective in regressing endometrial h yperplasia and in preventing the recurrence during 31 months follow up.