C. Prevedourakis et al., Breast cancer tamoxifen therapy and uterine problems, 7TH CONGRESS OF THE EUROPEAN SOCIETY FOR GYNAECOLOGICAL ENDOSCOPY, 1998, pp. 137-141
Forty three women operated for breast cancer in the past (22 premenopausal
and 21 post menopausal)treated with tamoxifen 20mg daily for 1 to 12 years
were submitted in the study,The protocol included physical examination, vag
inal ultrasound, diagnostic hysteroscopy and dilatation and curretage with
histology,Thirty one of the cases were asymptomatic (16 premenopausal and 1
5 postmenopausal) and 12 presented uterine bleeding (6 premenopausal and 6
postmenopausal) or 27.9% Simple hyperplasia with no atypia was found in 17
cases (39.5%), endometrial polyps in 8 cases (18.6%) with no malignancy,whi
le no endometrial cancer was found in all the presented cases.