A case of accidental intracranial penetration of a 29-cm-long portion of na
sogastric tube (NGT) in a 27-year-old female victim of a severe homicidal s
kull and brain trauma is reported. Accidental penetration of the NGT occurr
ed through a large fracture of the ethmoid lamina cribrosa. In addition to
a systematic review of previously reported cases, circumstantial data, clin
ical aspects, and autopsy data have been analyzed to draw medicolegal consi
derations concerning the connection between death and insertion of an NGT,
which may also contribute to the ascertaining of any possible professional
responsibility of medical staff, in a case fraught with numerous legal comp
lications.