Me. Wylie et al., Age at onset in geriatric bipolar disorder - Effects on clinical presentation and treatment outcomes in an inpatient sample, AM J GER PS, 7(1), 1999, pp. 77-83
The authors report on 62 inpatients over age 60 who met DSM-III-R criteria
for bipolar disorder, divided into early- and late-onset groups by their me
dian age at lifetime onset, 49 years, in order to examine differences in de
mographic and clinical characteristics, treatment parameters, and outcome i
n the two groups during a short-term hospitalization. The late-onset group
was more likely to have psychotic features and to demonstrate cerebrovascul
ar risk/burden. However, both groups had similar and highly significant imp
rovements in the Brief Psychiatric Rating Scale, Global Assessment Scale, a
nd the Mini-Mental State Exam, and 87% were able to be discharged to settin
gs no more restrictive than those at admission.