The increased prevalence of hypertension in the elderly should not be consi
dered a normal consequence of aging. The majority of older patients have el
evated systolic blood pressure. The risk of developing coronary disease and
heart failure increases as the systolic blood pressure increases, but anti
hypertensive treatment is successful in lowering the risk of cardiovascular
and cerebrovascular disease.
Despite the documented success of antihypertensive therapy in treating hype
rtension in clinical trials, the reality is that in the general population,
the control of hypertension is very inadequate. The most recent National H
ealth and Nutrition Examination Survey (NHANES) found that only 27.4% of th
e hypertensive population has blood pressure controlled to 140/90 mm I-Ig o
r less; The Sixth Report of the Joint National Committee on the Detection,
Awareness, and Treatment of Hypertension (JNC-VI) addresses these problems
and provides guidelines for management.
A major management emphasis advocated in JNC-VI is stratifying patients int
o risk groups according to overall cardiovascular risk and the presence of
target organ damage. Lifestyle modifications are stressed for all patients
with hypertension, and diuretics and long-acting calcium channel blockers a
re endorsed as appropriate first-line agents in older patients with isolate
d systolic hypertension. The report also provides compelling indications fo
r the use of certain drugs, advocates use of long-acting agents in order to
increase compliance, and recommends use of low-dose drug combinations that
can increase efficacy and safety, all important considerations in the olde
r patient with hypertension. The role of hypertension specialists in managi
ng difficult-to-treat cases is also stressed.
Systolic hypertension in the elderly is a disease that confers significant
cardiovascular risk. Several treatment options are available for managing i
solated systolic hypertension and to decrease cardiovascular morbidity and
mortality.