PURPOSE: We studied the intermediate-term clinical experience with the Ahme
d Glaucoma Valve implant (New World Medical, Inc, Rancho Cucamonga, Califor
nia).
METHODS: In this multicenter, retrospective case series, we studied 159 eye
s (144 patients) treated with the Ahmed Glaucoma Valve with a mean +/- SEM
(standard error of mean) follow-up of 13.4 +/- 0.7 months (range, 4 to 44 m
onths). The mean +/- SEM age was 60.9 +/- 1.9 years (range, 0.1 to 103 year
s). Surgical success was defined as intraocular pressure less than 22 mm Hg
and greater than 5 mm Hg without additional glaucoma surgery and without l
oss of light perception. Postoperative use of antiglaucoma medications was
not a criterion for success or failure. The definition of hypotony was intr
aocular pressure of 5 mm Hg or less in two consecutive visits.
RESULTS: Intraocular pressure was reduced from a mean of 32.7 +/- 0.8 mm Hg
before surgery to 15.9 +/- 9.6 mm Hg (P < .0001) at the most recent follow
-up after surgery. The number of antiglaucoma medications was decreased fro
m 2.7 +/- 0.1 before surgery to 1.1 +/- 0.1 after surgery (P < .0001). The
cumulative probability of success was 87% at 1 year and 75% at 2 years afte
r surgery (Kaplan-Meier life table analysis). Postoperatively, 24 (15%) of
159 eyes had intraocular pressure greater than or equal to 22 mm Hg. The vi
sual acuity was improved or within one Snellen line in 131 eyes (82%). Comp
lications occurred in 75 eyes (47%), the majority of which did not affect s
urgical outcome. The most common complication was obstruction of the tube,
which was observed in 17 eyes (11%). Transient postoperative hypotony was f
ound in 13 eyes (8%).
CONCLUSIONS: The Ahmed Glaucoma Valve implant is effective in lowering intr
aocular pressure, and postoperative hypotony is not commonly associated wit
h this implant. (C) 1999 by Elsevier Science Inc. All rights reserved.