Parameter estimation of an enzyme kinetic system using computer algebra techniques

Citation
M. Bayram et B. Yildiz, Parameter estimation of an enzyme kinetic system using computer algebra techniques, APPL MATH C, 99(1), 1999, pp. 93-98
Citations number
31
Categorie Soggetti
Engineering Mathematics
Journal title
APPLIED MATHEMATICS AND COMPUTATION
ISSN journal
00963003 → ACNP
Volume
99
Issue
1
Year of publication
1999
Pages
93 - 98
Database
ISI
SICI code
0096-3003(19990301)99:1<93:PEOAEK>2.0.ZU;2-Z
Abstract
A procedure for fitting enzyme kinetic data directly to the flux equation w as described. It involves choosing parameters that minimize the sum of the squares of deviations due to errors in s, the substrate concentration at ti me t. Estimates of the standard errors of the parameters are provided using computer algebra and numerical analysis techniques. (C) 1999 Elsevier Scie nce Inc. All rights reserved.