Chemical and enzymatic synthesis of glycoconjugates 5: One-pot regioselective synthesis of bioactive galactobiosides using a CLONEZYME (TM) thermophilic glycosidase library
J. Li et al., Chemical and enzymatic synthesis of glycoconjugates 5: One-pot regioselective synthesis of bioactive galactobiosides using a CLONEZYME (TM) thermophilic glycosidase library, BIOORG MED, 9(1), 1999, pp. 35-38
Enzymatic synthesis of galactobiosides using a versatile CLONEZYME((TM)) th
ermostable glycosidase library was studied. One-pot transglycosylation reac
tions were demonstrated to synthesize beta(1-->4), beta(1-->6), and alpha(1
-->6) disaccharide sequences with high regioselectivity and moderate to hig
h yields. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.