Cleavage of L-leucine-containing dipeptides by Clostridium butyricum

Authors
Khelifa, N Brik, M Tessedre, AC De Rocquigny, H Roques, BP Courtieu, J Rimbault, A
Citation
N. Khelifa et al., Cleavage of L-leucine-containing dipeptides by Clostridium butyricum, BIOORG MED, 9(1), 1999, pp. 109-112
Citations number
18
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
9
Issue
1
Year of publication
1999
Pages
109 - 112
Database
ISI
SICI code
0960-894X(19990104)9:1<109:COLDBC>2.0.ZU;2-8
Abstract
The ability of Clostridium butyricum cultures to hydrolyze three L-leucine- containing dipeptides (Leu-Leu, Leu-Gly and Gly-Leu) in a synthetic minimal medium is demonstrated by using gas chromatography coupled with mass spect rometry. The C-13 nuclear magnetic resonance and a labeled dipeptide L-[1-C -13]Leu-Gly were used to confirm this activity. (C) 1998 Elsevier Science L td. All rights reserved.