Citation
Jg. Ondeyka et al., Coprophilin: An anticoccidial agent produced by a dung inhabiting fungus, BIOORG MED, 8(24), 1998, pp. 3439-3442
Citations number
7
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X
→ ACNP
Volume
8
Issue
24
Year of publication
1998
Pages
3439 - 3442
Database
ISI
SICI code
0960-894X(199812)8:24<3439:CAAAPB>2.0.ZU;2-P
Abstract
Coprophilin, a decalin pentanedienoic acid methyl ester, was isolated from
an unidentified fungus by bioassay guided separation. It inhibited (MIC = 1
.5 mu M) the growth of Eimeria tenella in an in vitro assay. The isolation,
structure elucidation, absolute stereochemistry and biology are described.
(C) 1998 Elsevier Science Ltd. All rights reserved.