Anti-HIV coumarins from Calophyllum seed oil

Authors
Spino, C Dodier, M Sotheeswaran, S
Citation
C. Spino et al., Anti-HIV coumarins from Calophyllum seed oil, BIOORG MED, 8(24), 1998, pp. 3475-3478
Citations number
9
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
8
Issue
24
Year of publication
1998
Pages
3475 - 3478
Database
ISI
SICI code
0960-894X(199812)8:24<3475:ACFCSO>2.0.ZU;2-Y
Abstract
The seeds of Calophyllum cerasiferum Vesque (Family Clusiaceae), and Caloph yllum inophyllum Linn. (Family - Clusiaceae) contain several known coumarin s, among which were the potent HIV reverse transcriptase inhibitors costato lide and inophyllum P. Calophyllum cerasiferum contained (-)-calanolide B a s its major coumarin constituent in significant amount and thus constitute a renewable source of this compound. (C) 1998 Elsevier Science Ltd. All rig hts reserved.