Tracermer (TM) signal generators: An arborescent approach to the incorporation of multiple chemiluminescent labels

Authors
Adamczyk, M Fishpaugh, J Mattingly, PG Shreder, K
Citation
M. Adamczyk et al., Tracermer (TM) signal generators: An arborescent approach to the incorporation of multiple chemiluminescent labels, BIOORG MED, 8(24), 1998, pp. 3595-3598
Citations number
7
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
8
Issue
24
Year of publication
1998
Pages
3595 - 3598
Database
ISI
SICI code
0960-894X(199812)8:24<3595:T(SGAA>2.0.ZU;2-8
Abstract
The synthesis, conjugation, and chemiluminescent evaluation of zero, first, and second order acridinium-based Tracermer(TM) signal generators are desc ribed. Members of this family of labels have potential use as tracers in di agnostic assays and an structurally similar to arborol dendrimers. Tracerme r(TM)-BSA conjugates showed up to a sixfold increase in light emission comp ared to the normal acridinium label. (C) 1998 Elsevier Science Ltd. All rig hts reserved.