Sixty-five abdominal computed tomography (CT) scans of 54 systemic lup
us erythematosus (SLE) patients mere retrospectively evaluated togethe
r with their clinical records. This was to assess the spectrum of CT f
indings and to determine the value of abdominal CT in this group of pa
tients. Over a 3.5-year period, abdominal CT scans had been requested
for suspected renal vein or inferior vena cava thrombosis (n = 52, 80%
), sepsis, mesenteric ischaemia, Conn's syndrome, evaluation of hepato
splenomegaly, portal hypertension and hydronephrosis. The most frequen
t indication for CT was suspected renal vein thrombosis (RVT). An SLE
patient with previously stable renal function who rapidly develops nep
hrotic syndrome with deteriorating renal function has an increased ris
k of thromboembolic phenomenon. Also, renal vein thrombosis is difficu
lt to diagnose clinically and prompt anticoagulation can help preserve
remaining renal function. Of those with suspected RVT, two had RVT on
ly and five had thrombosis in both renal veins and inferior vena cava.
Two patients had CT features strongly suggestive of mesenteric ischae
mia, one had bilateral hydronephrosis thought to be secondary to lupus
cystitis and CT confirmed two abdominal abscesses. Other incidental C
T findings were: subscapular renal haematoma, overall enlargement or d
iminution of renal size, serositis, bowel wall thickening, splenic, he
patic and pancreatic enlargement and mild para-aortic lymphadenopathy.
Abdominal CT revealed many diverse findings and aided the management
of these SLE patients.