New lipid formulations of amphotericin B - AmBisome, Amphotec, and Abelcet
- have dramatically decreased the toxicity associated with amphotericin B a
nd have made this group of agents the treatment of choice for visceral leis
hmaniasis, An agent of a completely different chemical class, the aminoglyc
oside aminosidine, was 97% curative in India. This agent too may be used fo
r visceral leishmaniasis, Curr Opin Infect Dis 11:707-710. (C) 1998 Lippinc
ott Williams & Wilkins.