The development of auditory event related potentials in the rhesus monkey (Macaca mulatta)

Auditory event related potentials were recorded from neonatal, 3-month, and 3-year old rhesus monkeys. Auditory brainstem evoked responses (ABRs) were reliably recorded at all ages. ABR latencies decreased with age. Age effec ts were greater the moi-e centrally generated the wave. Wave I amplitude de c,eased with age, Wave II increased, and Wave IV remained about the same. S timulus rate effects were greater in neonates than older monkeys. Stimulus frequency also affected the ABR, but not differentially as a function of ag e. Recording montage had a significant effect on the recorded waveform. Wav e I tended to be larger in amplitude in horizontal recordings and front-bac k recordings, while the later waves were relatively mole prominent in more vertical montages. Middle latency evoked responses and late potentials were less reliably recorded than the ABR. Their reproducibility improved with a ge. Auditory event related potentials are promising measures of auditory fu nction for research requiring nonhuman primate models of the the developing human. (C) 1999 John Wiley & Soils, Inc.