Treatment options for chronic prostatitis due to vancomycin-resistant Enterococcus faecium

Prostatitis due to vancomycin-resistant enterococci has not been previously described. Reported here is a case of chronic prostatitis due to Enterococ cus faecium, resistant to vancomycin, ampicillin, ciprofloxacin and doxycyc line, in a 42-year-old liver transplant recipient. Treatment with a combina tion of rifampin and nitrofurantoin for 6 weeks resulted in long-lasting cu re. Other antimicrobial agents active in vitro against vancomycin-resistant enterococci, such as quinupristin/dalfopristin and chloramphenicol, are un likely to achieve sufficient prostatic tissue levels to be successfully uti lized for treatment of this condition.