Je. Scott, How rational histochemistry produced order out of chaos in the "amorphous ground substance" (with a little help from biochemistry, biophysics etc.), EUR J HIST, 42, 1998, pp. 29-34
From an amorphous ground substance containing polymers of unknown compositi
on arranged in no particular pattern we have in about 50 years arrived at a
proposal where the very shape of the tissue and hence of the organism is d
etermined by newly discovered structures, the shape modules, in the ground
substance, which were demonstrated by histochemical techniques interpreted
on rational biophysical and chemical principles.