Multienzyme system for synthesis of the sialylated Thomsen-Friedenreich antigen determinant

Authors
Gambert, U Thiem, J
Citation
U. Gambert et J. Thiem, Multienzyme system for synthesis of the sialylated Thomsen-Friedenreich antigen determinant, EUR J ORG C, (1), 1999, pp. 107-110
Citations number
13
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434193X → ACNP
Issue
1
Year of publication
1999
Pages
107 - 110
Database
ISI
SICI code
1434-193X(199901):1<107:MSFSOT>2.0.ZU;2-Z
Abstract
A combined sequential use of beta-galactosidase from bovine testes together with alpha 2-3-sialyltransferase from porcine liver including cofactor reg eneration transforms GalNAc alpha 1-OThr by a multistep one-pot reaction in to the sialylated Thomsen-Friedenreidh antigen determinant Neu5Ac alpha 2-3 Gal beta 1-3GalNAc alpha 1-OThr.