Vg. Shalyapina et al., MODIFICATION OF BEHAVIORAL-EFFECTS OF COR TICOTROPIN-RELEASING HORMONE BY EARLY POSTNATAL INJECTIONS OF CORTICOSTEROIDS, Zurnal vyssej nervnoj deatelnosti im. I.P. Pavlova, 47(1), 1997, pp. 130-135
The action of intrastriatal administration of corticotropin-releasing
hormone (CRH) on behaviour of male rats with early postnatal hydrocort
isone injections was studied in open field experiments. Bilateral CRH
administration into neostriatum significantly decreased the locomotor
and exploratory activity, Rats which had been injected with hydrocorti
sone within the first 5 days of life were characterized by increased l
ocomotion, but the anxiogenic action of CRH in these animals was not o
bserved.