SEVERE MESNA-INDUCED ERUPTION IN A PATIENT WITH POLYARTERITIS-NODOSA

Authors
DESCAMPS V MARCK Y LEJOYEUX F HAYEM G BOUSCARAT F GROSSIN M CRICKX B BELAICH S
Citation
V. Descamps et al., SEVERE MESNA-INDUCED ERUPTION IN A PATIENT WITH POLYARTERITIS-NODOSA, EJD. European journal of dermatology, 7(3), 1997, pp. 175-176
Citations number
13
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
EJD. European journal of dermatology → ACNP
ISSN journal
11671122
Volume
7
Issue
3
Year of publication
1997
Pages
175 - 176
Database
ISI
SICI code
1167-1122(1997)7:3<175:SMEIAP>2.0.ZU;2-T
Abstract
Mesna (2-mercaptoethane sulfonate) is used to prevent cyclophosamide-a ssociated urotoxicity, Drug eruptions from mesna have been reported on ly rarely, and were usually minor macular or urticarial rashes. A case of a severe, mesna-induced eruption with detachment of 20% of the ski n is reported in a patient with polyarteritis nodosa. From the clinica l course and a positive intradermal skin test with mesna (0.1%), mesna was thought to be the cause.