Spirituality is an important though often neglected aspect of pain in patie
nts with human immunodeficiency virus (HIV) and/or cancer, for both patient
s and nurses. The spiritual domain involves: (1) meaning, (2) hope and (3)
love and relatedness. The author examines spiritual aspects of pain in pers
ons with HIV and/or cancer, as supported by the literature, Understanding s
piritual aspects of pain carries implications for nursing. One of these imp
lications is that it is important for the nurse to be closer to his/her own
spirit in order to be there for the patient in pain. Other nursing implica
tions include spiritual assessment and interventions, such as presence, att
entive listening, acceptance and judicious self-disclosure, for promoting c
omfort and diminishing pain.