Expression of platelet-derived endothelial cell growth factor (PD-ECGF) related to angiogenesis in ovarian endometriosis

Authors
Fujimoto, J Sakaguchi, H Hirose, R Tamaya, T
Citation
J. Fujimoto et al., Expression of platelet-derived endothelial cell growth factor (PD-ECGF) related to angiogenesis in ovarian endometriosis, J CLIN END, 84(1), 1999, pp. 359-362
Citations number
33
Categorie Soggetti
Endocrynology, Metabolism & Nutrition","Endocrinology, Nutrition & Metabolism
Journal title
JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM
ISSN journal
0021972X → ACNP
Volume
84
Issue
1
Year of publication
1999
Pages
359 - 362
Database
ISI
SICI code
0021-972X(199901)84:1<359:EOPECG>2.0.ZU;2-L
Abstract
Platelet-derived endothelial cell growth factor (PD-ECGF) is expressed in t he lining epithelial cells of ovarian endometriomas, and in interstitial ce lls of the subepithelial area with angiogenesis. The expression of PD-ECGF persists in endometriotic endometrium during the menstrual cycle. This migh t suggest that PD-ECGF contributes to the growth of ovarian endometriomas v ia subepithelial angiogenesis independently of the sex steroidal milieu.