Sedimentation velocity analysis is a powerful tool for the investigati
on of biological macromolecules under a wide range of solution conditi
ons. If carefully applied, it can be an effective tool for the charact
erization of interacting systems in solution. It is rapidly becoming a
method of choice among the biotechnology community. In recent years,
there have been notable advances in the ease of acquisition and analys
is of analytical ultracentrifugation data.