Jle. Reubsaet et al., Analytical techniques used to study the degradation of proteins and peptides: physical instability, J PHARM B, 17(6-7), 1998, pp. 979-984
The physical instability of proteins and peptides as well as the various an
alytical techniques used to study the various aspects of physical instabili
ty have been reviewed. Physical instability of proteins and peptides involv
e changes in secondary, tertiary and quaternary structures of these compoun
ds. After a general introduction of the subject the literature data of thes
e changes and their analytical aspects have been summarized in a Table. (C)
1998 Published by Elsevier Science B.V. All rights reserved.