Adrenal-renal portal circulation contributes to decrease in renal blood flow after renal artery stenosis in rats

The aim of the present study was to investigate a role of adrenal-renal por tal circulation (ARPC) in a decrease in renal blood now due to acute stenos is of the renal artery in rats. Animals were divided into three groups. In the control group (I), in order to eliminate the ARPC tissue between the ad renal gland and the ipsilateral kidney was cut. In the second and the third group (II) (III), left renal artery was stenosed by a silver clip (ID 0.40 mm). Then, in the group II, ARPC was surgically eliminated. In the group I II, prior to the elimination of ARPC, alpha-adrenergic receptors blockade w as produced by phentolamine administration. In the control group, ARPC elim ination did not influence either renal blood flow (RBF) or renal vascular r esistance (RVR). In the group II, elimination of ARPC caused increase in RB F and decrease in RVR In the group III elimination of ARPC influenced neith er RBF nor renal vascular resistance (RVR). Results of the present study pr ovide the functional evidence that catecholamines reaching the kidney throu gh ARPC, contribute to the decrease in RBF and increase in RVR during acute renal artery stenosis in the rat.