In this article we present data from our laboratory, and review the literat
ure available, on the potential association between HIV-1 and sperm. We foc
us on the use of PCR technology to answer this very important question, and
emphasise the importance of using highly purified sperm preparations. We c
onclude that the likelihood of HIV infection/association with viable mature
sperm is low. (C) 1998 Published by Elsevier Science Ireland Ltd. All righ
ts reserved.