Clinical efficacy of milbemycin oxime in the treatment of nasal mite infection in dogs

A multicentric clinical trial was done to evaluate the clinical efficacy of milbemycin oxime in the treatment of nasal mite (Pneumonyssoides caninum) infection in dogs. Milbemycin oxime was given to 70 dogs of different breed s, genders, and ages, with clinical signs associated with nasal mite infect ion. Twenty-five dogs had a verified infection, and 45 dogs had signs sugge stive of nasal mite infection. Milbemycin oxime was given at the dosage of 0.5 to 1.0 mg/kg body weight orally once a week for three consecutive weeks , One month after initiation of treatment, 68 of the dogs had no more clini cal signs associated with nasal mite infection.