Psychotic disorders, and especially schizophrenia, have to be consider
ed as a major public health problem : these disorders are characterize
d by a relatively high prevalence, an early age at onset, and a major
negative impact on the social adjustment. Owing to the lack of definit
e knowledge on the causal risk factors involved in the emergence of su
ch disorders, it seems currently difficult to develop primary preventi
ve programmes to reduce the incidence of these disorders. On the other
hand, the secondary prevention of psychotic disorders is probably und
er-developed. Some studies have suggested that the early recognition a
nd treatment of psychotic disorders might improve the outcome. Several
methodological problems limit the implementation of early interventio
n programmes. However preliminary studies have at least demonstrated t
he faisability of secondary prevention. It is nevertheless necessary t
o confirm that such strategies have a positive impact on the long-term
e course of the disorders, i.e. that they are able to modify the natur
al history of these disorders.