In severe vaginal malformations, when the distance between the upper v
aginal pouch and perineum is too long (6 cm or more), reconstruction o
f the vagina can be performed by colonic interposition or by long cuta
neous flaps obtained by the tissue expansion technique. Two female ado
lescents were treated using expanded labial skin flaps. Dissection and
anastomosis between the vaginal remnant and cutaneous tube was perfor
med by the transtrigonal approach. Results were satisfactory at 2.5-ye
ar follow-up. In our opinion, expanded labial skin-flap vaginoplasty h
as three main advantages: (1) it permits the construction of a large,
soft, well-vascularized neovagina using non-hair-bearing labial skin;
(2) it obviates postoperative dilations and prevents delayed stricture
s; and (3) a transtrigonal approach permits an easy vaginal dissection
and a careful, tension-free anastomosis.