PRELIMINARY-X-RAY CRYSTALLOGRAPHIC DATA FOR A MYOTOXIN FROM AGKISTRODON CONTORTRIX LATICINCTUS (BROAD-BANDED COPPERHEAD) VENOM

Authors
TREHARNE AC WHITE SP OWNBY CL DEARAUJO HSS FOUNDLING SI
Citation
Ac. Treharne et al., PRELIMINARY-X-RAY CRYSTALLOGRAPHIC DATA FOR A MYOTOXIN FROM AGKISTRODON CONTORTRIX LATICINCTUS (BROAD-BANDED COPPERHEAD) VENOM, Toxicon, 35(4), 1997, pp. 613-615
Citations number
12
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Toxicon → ACNP
ISSN journal
00410101
Volume
35
Issue
4
Year of publication
1997
Pages
613 - 615
Database
ISI
SICI code
0041-0101(1997)35:4<613:PCDFAM>2.0.ZU;2-W
Abstract
A Type II phospholipase A(2) myotoxin from Agkistrodon contortrix lati cinctus was purified to homogeneity and crystallized. The protein had only myotoxic activity. X-ray diffraction quality crystals were obtain ed by the hanging drop vapour diffusion method from a crystallization solution containing 2.0 M ammonium sulphate. X-ray data were collected to a resolution of 2.3 Angstrom, and the crystals are fully character ized. (C) 1997 Elsevier Science Ltd.