SIGNIFICANCE OF RCC IN HEMODIALYSIS-PATIE NTS COMPARED TO RENAL-ALLOGRAFT RECIPIENTS

The clinical relevance of de novo Renal Cell Cancer was compared in ch ronic hemodialysis patients and renal allograft recipients. Clinical c ourse of these patients was followed for 15 years. 21 of 788 patients who underwent radical nephrectomy were suffering from renal insufficie ncy at the time of surgery. Evaluated data included clinical symptoms, tumor histology and clinical course. 19 patients received chronic hem odialysis treatment. 7 patients demonstrated stable function of the al lograft. 92 % of patients receiving hemodialysis treatment did not sho w metastasis and none died of renal cell carcinoma. On the contrary, 7 1 % of patients who underwent renal transplantation showed advanced tu mor disease or metastasis. 3 patients have died of RCC. Aggressive tum or growth of RCC requieres close follow up in patients who received a renal allograft.