The presence of humic and fulvic acids in the Anticolana Valley (Fiuggi) wa
ter has been established. On the basis of th is evidence we investigated th
e capacity of Anticolana Valley (Fiuggi) water to dissolve renal calculi in
vitro. Crystals of calcium oxalate monohydrate to simulate a kidney stone
were prepared. Human renal stones of calcium oxalate monohydrate were obtai
ned by courtesy of the Division of Urology of 'La Sapienza' University (Rom
e), the Division of Urology of the University of Havana (Cuba) and the ASTI
F of Fiuggi. The study was performed using the Anticolana Valley (Fiuggi) w
ater, distilled water and tap water (ACEA, Rome), in a specially designed P
erspex apparatus. Each calculus was subjected to a water flow of 2 liters/2
4 h, The capacity of the Anticolana Valley (Fiuggi) water to dissolve human
and synthetic calculi was found to be much higher than that of distilled w
ater which in turn was significantly more effective than tap (ACEA) water.