PREPARATION AND REACTIONS OF 5-NITROMETHYL-GAMMA-TOCOPHEROL ACETATE

Authors
WITKOWSKI S MARKOWSKA A WALEJKO P
Citation
S. Witkowski et al., PREPARATION AND REACTIONS OF 5-NITROMETHYL-GAMMA-TOCOPHEROL ACETATE, Polish Journal of Chemistry, 71(4), 1997, pp. 449-453
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Polish Journal of Chemistry → ACNP
ISSN journal
01375083
Volume
71
Issue
4
Year of publication
1997
Pages
449 - 453
Database
ISI
SICI code
0137-5083(1997)71:4<449:PARO5A>2.0.ZU;2-V
Abstract
Nitration of a-tocopherol acetate 1b yielded 5-nitromethyl-gamma-tocop herol acetate 2b. The acetate 2b was converted to free phenol 2a by tr ansesterification in methanol. Reduction of 2b by NaBH4 in ethyl aceta te and methanol gave 5-(2-hydroxypropyl)-gamma-tocopherol 5a and 5-met hoxymethyl-gamma-tocopherol 6 respectively.