LYMPHOCYTE SUBPOPULATION EXPRESSION IN WOMEN - EFFECT OF EXERCISE ANDCIRCADIAN-RHYTHM

Citation
Eb. Zelazowska et al., LYMPHOCYTE SUBPOPULATION EXPRESSION IN WOMEN - EFFECT OF EXERCISE ANDCIRCADIAN-RHYTHM, Medicine and science in sports and exercise, 29(4), 1997, pp. 467-473
Citations number
30
Categorie Soggetti
Sport Sciences
ISSN journal
01959131
Volume
29
Issue
4
Year of publication
1997
Pages
467 - 473
Database
ISI
SICI code
0195-9131(1997)29:4<467:LSEIW->2.0.ZU;2-P
Abstract
It is well established that exercise affects immune responses in men, but little information is available for women. whether exercise-induce d immune responses are affected by circadian rhythm has not been deter mined. This study examined lymphocyte responses of women to exercise i n the morning (AM) and evening (PM). Lymphocytes expressing markers fo r T, B, and natural killer (NK) cells were identified by FACScan in bl ood samples collected before (baseline), immediately after, and 40 min after exercise (recovery). Absolute counts of all lymphocyte subpopul ations increased immediately after exercise, bur at recovery values we re below baseline counts. Circadian variations were noted in absolute counts for total T, helper/inducer T cells, and B cells. Although thes e counts were significantly higher in the PM, the magnitude of the imm une response to exercise was the same in the AM and PM. In contrast, n atural killer cells, both the relative counts and the magnitude of imm une response were higher in the AM. Thus, it appears that despite diff erences in baseline cell counts the overall exercise-induced response in most lymphocyte subpopulations is similar in the AM and PM.