Hierridin B and 2,4-dimethoxy-6-heptadecyl-phenol, secondary metabolites from the cyanobacterium Phormidium ectocarpi with antiplasmodial activity

Authors
Papendorf, O Konig, GM Wright, AD
Citation
O. Papendorf et al., Hierridin B and 2,4-dimethoxy-6-heptadecyl-phenol, secondary metabolites from the cyanobacterium Phormidium ectocarpi with antiplasmodial activity, PHYTOCHEM, 49(8), 1998, pp. 2383-2386
Citations number
18
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
49
Issue
8
Year of publication
1998
Pages
2383 - 2386
Database
ISI
SICI code
0031-9422(199812)49:8<2383:HBA2SM>2.0.ZU;2-H
Abstract
Bioassay guided fractionation of the lipophilic extract of the marine cyano bacterium Phormidium ectocarpi yielded a new natural product hierridin B an d the previously described compound 2,4-dimethoxy-6-heptadecyl-phenol. Both structures were secured by extensive spectroscopic analysis (1D and 2D NMR , MS, GC-MS, IR). The isolate (mixture) showed antiplasmodial activity towa rds Plasmodium falciparum. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.